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Home > Exhibitions > Classic cases of tuberculosis > Tuberculous pericarditis

Tuberculous pericarditis

Tuberculous pericarditis usually develops as a result of retrograde lymphatic spread of bacilli from tracheobronchial or mediastinal lymph nodes.
It is the most common cause of pericarditis in Africa, and the incidence has increased due to the HIV epidemic.

Tuberculosis of the pericardium (Case 811)

This patient would have presented with signs and symptoms of constrictive pericarditis. A "pericardial knock" may have been heard on auscultation.

These transverse sections of an adult heart show a late stage of tuberculous pericarditis.

These transverse sections of an adult heart show a late stage of tuberculous pericarditis.
The pericardial space is grossly widened by large areas of caseation in a shell of organised fibrosis - this would be clearly visible on echocardiogram.

 

When the bottle is reversed, adherent caseous lymph nodes are seen at the base of the heart.

When the bottle is reversed, adherent caseous lymph nodes are seen at the base of the heart.

 

Recent review

Mayosi BM, Burgess LJ & Doubell AF. Tuberculous Pericarditis. Circulation. 2005; 112: 3608-3616
available at http://circ.ahajournals.org/content/112/23/3608.long

Listen to a Pericardial knock

available at http://texasheart.org/Education/CME/explore/events/upload/HSPS18_PerKnock.mp3

See also

http://www.pathologylearningcentre.uct.ac.za/tuberculous-pericarditis